HCQS 200mg | rheumatoid arthritis – 30 TABS

KSh 750.00

HCQS 200mg contains Hydroxychloine sulfate, which mainly used in the treatment of systemic and discoid lupus erythematosus and rheumatoid arthritis. It is also used in the treatment of light-sensitive skin eruptions. In lupus erythematosus and rheumatoid arthritis, response to treatment may not be apparent for up to 6 months but if there is no improvement by then, treatment should be discontinued. Treatment is usually started with 400 mg daily in divided doses with meals. Doses are reduced to the minimum effective dose for maintenance; this is usually 200 to 400 mg daily but should not exceed 6.5 mg/kg daily (or 400 mg daily whichever is the smaller).

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Description

Rheumatoid arthritis.

Hydroxychloroquine and chloroquine are used as antirheumatic drugs in the management of rheumatoid arthritis in an attempt to suppress the rate of cartilage erosion or alter the course of the disease.1They are considered to be less effective than the other disease-modifying antirheumatic drugs (DMARDs) but they are usually better tolerated and so may be preferred in patients with milder forms of the disease.2Additional benefit has been obtained using antimalarials with other DMARDs especially methotrexate and sulfasalazine,3-5although adverse effects may be more common.

Generally the lowest effective dose should be used for maintenance to minimise toxicity; for hydroxychloroquine sulfate this should not exceed 6.5 mg/kg lean body-weight daily. Daily doses of 200 or 400 mg are commonly used but one study indicates that there is little advantage in using the higher dose.

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